Now showing items 1-20 of 46

    • Wilson, Carlos; Muñoz Palma, Ernesto; Henríquez, Daniel R.; Palmisano, Ilaria; Núñez González, Marco; Di Giovanni, Simone; González Billault, Christian (Soc Neuroscience, 2016)
      Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca2+, a broad intracellular second messenger, promotes both Rac1 ...
    • Baas, Peter W.; González Billault, Christian (2012)
      This essay attempts to capture the spirit of our recent meeting in Chile entitled "Emerging Concepts in Neuronal Cytoskeleton." The purpose of the meeting was to bring together scientists from South American countries with ...
    • Shirao, Tomoaki; González Billault, Christian (International Society for Neurochemistry, 2013-07)
      endritic spines are small protrusions emerging from their parent dendrites, and their morphological changes are involved in synaptic plasticity. These tiny structures are composed of thousands of different proteins belonging ...
    • Amorim Neto, Dionisio Pedro; Pelegrini Bosque, Beatriz; Pereira de Godoy, Joao Vitor; Vieira Rodrigues, Paulla; Meneses, Darío Donoso; Tostes, Katiane; Costa Tonoli, Celisa Caldana; Carvalho, Hernandes Faustino de; González Billault, Christian; Castro Fonseca, Matheus de (Elsevier, 2022)
      The gut microbiota influence neurodevelopment, modulate behavior, and contribute to neurodegenerative disorders. Several studies have consistently reported a greater abundance of Akkermansia muciniphila in Parkinson disease ...
    • Mendoza Naranjo, Ariadna; González Billault, Christian; Maccioni Baraona, Ricardo (COMPANY OF BIOLOGISTS LTD, 2006-10-30)
      A number of psychiatric and neurodegenerative disorders, such as Alzheimer’s disease, are characterized by abnormalities in the neuronal cytoskeleton. Here, we find that the enhancement in actin polymerization induced ...
    • Jiménez Mateos, Eva; Wandosell, Francisco; Orly, Reiner; Avila, Jesús; González Billault, Christian (PORTLAND PRESS LTD, 2005-07-15)
      For neuronal migration to occur, the cell must undergo morphological changes that require modifications of the cytoskeleton. Several different MAPs (microtubule-associated proteins) or actin-binding proteins are proposed ...
    • Bórquez Muñoz, Daniel; Olmos, Cristina; Álvarez, Sebastián; Genova, Alex Di; Maass Sepúlveda, Alejandro; González Billault, Christian (Elsevier, 2013)
      Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase predominantly active in the nervous system where it regulates several processes such as neuronal migration, cytoskeletal dynamics, axonal ...
    • González Silva, Carolina; Vera, Jorge; Bono Merino, María Rosa; González Billault, Christian; Baxter, Brooke; Hansen, Anne; López, Robert; Gibson, Emily A.; Restrepo, Diego; Bacigalupo Vicuña, Juan (PLoS ONE, 2013)
      The Ca2+-activated Cl2 channel is considered a key constituent of odor transduction. Odorant binding to a specific receptor in the cilia of olfactory sensory neurons (OSNs) triggers a cAMP cascade that mediates the opening ...
    • Posada Duque, Rafael; Ramírez, Omar A.; Härtel, Steffen; Inestrosa, Nibaldo C.; Bodaleo, Felipe; González Billault, Christian; Kirkwood, Alfredo; Cardona Gómez, Gloria (Birkhauser Verlag AG, 2017)
      © 2016, Springer International Publishing. CDK5 is a serine/threonine kinase that is involved in the normal function of the adult brain and plays a role in neurotransmission and synaptic plasticity. However, its over-regulation ...
    • Utreras Puratich, Elías; Henríquez, Daniel R.; Contreras Vallejos, Erick; Olmos, Cristina; Di Genova, Alex; Maass Sepúlveda, Alejandro; Kulkarni, Ashok B.; González Billault, Christian (2013)
      Rap1 signaling is important for migration, differentiation, axonal growth, and during neuronal polarity. Rap1 can be activated by external stimuli, which in turn regulates specific guanine nucleotide exchange factors such ...
    • González Billault, Christian; Núñez, T.; Wilson, C. (Wiley & Sons, 2015)
    • Wilson, Carlos; Núñez González, Marco; González Billault, Christian (Company of Biologists Ltd., 2015)
      Reactive oxygen species (ROS) produced by the NADPH oxidase (NOX) complex play important physiological and pathological roles in neurotransmission and neurodegeneration, respectively. However, the contribution of ROS to ...
    • Contreras Vallejos, Erick; Utreras Puratich, Elías; González Billault, Christian (2012)
    • Parra, Mario Alfredo; Báez, Sandra; Sedeño, Lucas; González Campo, Cecilia; Santamaría García, Hernando; Aprahamian, Iván; Bertolucci, Paulo H. F.; Bustin, Julián; Camargos Bicalho, María Aparecida; Cano Gutiérrez, Carlos; Caramelli, Paulo; Chaves, Marcia L. F.; Cogram, Patricia; Costa Beber, Bárbara; Court, Felipe A.; Cruz de Souza, Leonardo; Custodio, Nilton; Damián, Andrés; Cruz, Myriam de la; Rodríguez, Roberta Diehl; Dozzi Brucki, Sonia María; Fajersztajn, Lais; Farías Gontupil, Gonzalo Andrés; Felice, Fernanda G. de; Ferrari, Raffaele; Ferreira de Oliveira, Fabricio; Ferreira, Sergio T.; Ferretti, Ceres; Figueredo Balthazar, Marcio Luiz; Ferreira Frota, Norberto Anizio; Fuentes, Patricio; García, Adolfo A.; García, Patricia J.; De Gobbi Porto, Fábio Henrique; Duque Peñailillo, Lissette; Engler, HenryWilly; Maier, Irene; Mata, Ignacio F.; González Billault, Christian; López, Oscar L.; Morelli, Laura; Nitrini, Ricardo; Quiroz, Yakeel T.; Guerrero Barragán, Alejandra; Huepe, David; Pio, Fabricio Joao; Kimie Suemoto, Claudia; Kochhann, Renata; Kochen, Silvia; Kumfor, Fiona; Lanata, Serggio; Miller, Bruce; Mansur, Leticia Lessa; Hosogi, Mirna Lie; Lillo, Patricia; Guerra, Jorge Llibre; Lira, David; Lopera, Francisco; Comas, Adelina; Ávila Funes, José Alberto; Sosa, Ana Luisa; Ramos, Claudia; França Resende, Elisa de Paula; Snyder, Heather M.; Tarnanas, Ioannis; Yokoyama, Jenifer; Llibre, Juan; Cardona, Juan Felipe; Possin, Kate; Kosik, Kenneth S.; Montesinos, Rosa; Moguilner, Sebastián; Solís, Patricia Cristina Lourdes; Ferretti Rebustini, Renata Eloah de Lucena; Ramírez, Jerónimo Martin; Matallana, Diana; Mbakile Mahlanza, Lingani; Marques Ton, Alyne Mendonça; Tavares, Ronnielly Melo; Miotto, Eliane C.; Muniz Terrera, Graciela; Muñoz Nevárez, Luis Arnoldo; Orozco, David; De Oliveira, Maira Okada; Piguet, Olivier; Caipa, Maritza Pintado; Piña Escudero, Stefanie Danielle; Schilling, Lucas Porcello; Rodrigues Palmeira, André Luiz; Sanches Yassuda, Mônica; Santacruz Escudero, José Manuel; Serafim, Rodrigo Bernardo; Smid, Jerusa; Slachevsky, Andrea; Serrano, Cecilia; Soto Añari, Marcio; Takada, Leonel Tadao; Grinberg, Lea Tenenholz; Teixeira, Antonio Lucio; Barbosa, Maira Tonidandel; Trépel, Dominic; Ibáñez, Agustín (Wiley, 2021)
      Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed ...
    • Palacios Garcia, Ismael Jose (Universisdad de Chile, 2013)
      El estrés prenatal es un factor de riesgo en el desarrollo de condiciones neuropsiquiatricas como la depresión y la esquizofrenia. Mas aun, estos efectos pueden perdurar hasta la adultez causado predisposición a adquirir ...
    • Kahn, Olga I.; Sharma, Vandana; González Billault, Christian; Baas, Peter W. (Amer Soc Cell Biology, 2015)
      ABSTRACT Kinesin-5 is a slow homotetrameric motor protein best known for its essential role in the mitotic spindle, where it limits the rate at which faster motors can move microtubules. In neurons, experimental suppression ...
    • Muñoz Llancao, Pablo; Henríquez, Daniel R.; Wilson, Carlos; Bodaleo, Felipe; Boddeke, Erik W.; Lezoualc'h, Frank; Schmidt, Martina; González Billault, Christian (Soc. Neuroscience, 2015)
      Acquisition of neuronal polarity is a complex process involving cellular and molecular events. The second messenger cAMP is involved in axonal specification through activation of protein kinase A. However, an alternative ...
    • González Billault, Christian (John Wiley and Sons Inc., 2017)
    • Urrutia, Pamela J.; Aguirre, Pabla; Esparza, Andrés; Tapia, Victoria; Mena, Natalia P.; Arredondo Olguín, Miguel Armando; González Billault, Christian; Núñez González, Marco (2013)
      Inflammation and iron accumulation are present in a variety of neurodegenerative diseases that include Alzheimer’s disease and Parkinson’s disease. The study of the putative association between inflammation and iron ...
    • Quintanilla, Rodrigo A.; Orellana, Daniel I.; González Billault, Christian; Maccioni Baraona, Ricardo (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004-04-15)
      Inflammation is a process that has been actively related with the onset of several neurodegenerative disorders including Alzheimer disease (AD). However, the precise implications of inflammatory response for neurodegeneration ...